Understanding Glucosamine and ChondroitinA joint is the area where two bones make contact and allows movement. In a healthy movable joint, the ends of bones are covered by a specialized type of smooth cartilage and lubricated by synovial fluid that allows the bones to glide over each other. Joints are largely responsible for providing stability and flexibility to the skeleton and can support a large amount of force placed on our bodies during daily activities. Glucosamine and Chondroitin are both parts of key structural components found in cartilage. As a highly charged polyanion, Chondroitin Sulfate retains water in the connective tissue. Glucosamine is considered an important molecular component of glycosaminoglycans, which is a key structural component in cartilage. Joints support a large amount of force placed on our bodies and aid in the performance of daily activities.